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pentobarbital will lessen the extent or outcome of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Steer clear of coadministration of lefamulin with solid or average CYP3A inducers unless the reward outweighs challenges. Keep an eye on for lowered efficacy.Watch Intently (1)pentobarbital wil